Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine-needle aspiration biopsy diagnosis of gastrointestinal stromal tumors using morphology, immunocytochemistry, and mutational analysis of c-kit.

Cancer - 25 Aug 2001

Rader A E, Avery A, Wait C L, McGreevey L S, Faigel D, Heinrich M C

Abstract excerpt

BACKGROUND: Differentiating gastrointestinal stromal tumors (GISTs) from other intramural mesenchymal tumors of the GI tract on fine-needle aspiration biopsies (FNABs) is difficult. Recent studies have shown that GISTs are immunophenotypically and genetically distinct. GISTs exhibit consistent immunohistochemical expression of CD-117 (KIT) and often express activating mutations of this protooncogene. The aim of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Needle
Share to Carcinoma
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Point Mutation

Share to Proto-Oncogene Proteins c-kit

Share to Stomach Neoplasms

Share to Stromal Cells

Source

Identifiers

PMID: 11507701
DOI: 10.1002/cncr.9041

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine-needle aspiration biopsy diagnosis of gastrointestinal stromal tumors using morphology, immunocytochemistry, and mutational analysis of c-kit.PMID 11507701Read ↗

Analysis of KIT mutation and protein expression in fine needle aspirates of gastrointestinal stromal/smooth muscle tumors.Semantic proximity Read ↗

Diagnosis of gastrointestinal stromal tumors from minute specimens: cytomorphology, immunohistochemistry, and molecular diagnostic findings.Semantic proximity Read ↗

c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant.Semantic proximity Read ↗

Succinate dehydrogenase-deficient gastrointestinal stromal tumor of stomach diagnosed by endoscopic ultrasound-guided fine-needle biopsy: Report of a distinct subtype in cytology.Semantic proximity Read ↗

Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade.Semantic proximity Read ↗

Epithelioid gastrointestinal stromal tumor of the stomach with liver metastases in a 12-year-old girl: aspiration cytology and molecular study.Semantic proximity Read ↗

Immunohistochemical profile and c-kit mutations in gastrointestinal stromal tumors.Semantic proximity Read ↗

Comparative validation of c-kit exon 11 mutation analysis on cytology samples and corresponding surgical resections of gastrointestinal stromal tumours.Semantic proximity Read ↗

Diagnosis of gastrointestinal stromal tumors: A consensus approach.Semantic proximity Read ↗

A c-kit-negative gastrointestinal stromal tumor with a platelet-derived growth factor receptor alpha mutation.Semantic proximity Read ↗

Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity.Semantic proximity Read ↗

Diagnosing gastrointestinal stromal tumors: The utility of fine-needle aspiration cytology versus biopsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.