Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway

26 Sept 2018

Abstract excerpt

Coxsackievirus B3 (CVB3) infection is the leading cause of viral myocarditis, but effective vaccines and antiviral therapies against CVB3 infection are still lacking. It is important to understand the precise interactions between host and virus for the rational design of effective therapies. During infection, CVB3 disrupts and exploits host lipid metabolism to promote excessive lipid accumulation, which benefits...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to RNA regulation and disease
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30258014
DOI: 10.1128/jvi.01060-18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK PathwayPMID 30258014Read ↗

Hepatitis C virus nonstructural 4B protein modulates sterol regulatory element-binding protein signaling via the AKT pathway.Semantic proximity Read ↗

MicroRNAs Regulate the Pathogenesis of CVB3-Induced Viral MyocarditisSemantic proximity Read ↗

A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum TargetingSemantic proximity Read ↗

The roles of different microRNAs in the regulation of cholesterol in viral hepatitisSemantic proximity Read ↗

Role of non-coding RNAs in the pathogenesis of viral myocarditisSemantic proximity Read ↗

SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19Semantic proximity Read ↗

MicroRNA-22-3p displaces critical host factors from the 5′ UTR and inhibits the translation of Coxsackievirus B3 RNASemantic proximity Read ↗

A Kidnapping Story: How Coxsackievirus B3 and Its Host Cell InteractSemantic proximity Read ↗

A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variantsSemantic proximity Read ↗

A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variantsSemantic proximity Read ↗

Metabolic Syndrome and Viral Pathogenesis: Lessons from Influenza and CoronavirusesSemantic proximity Read ↗

Transcriptomic Analysis Reveals Both Coxsackievirus B3 Woodruff and GD Strain Using Similar Key Genes to Induce FoxO Signaling Pathway Activation in HeLa CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.