Article
A study of the MTHFR gene polymorphism C677T in colorectal cancer.
Clinical colorectal cancer - 1 Jan 2009
Derwinger Kristoffer, Wettergren Yvonne, Odin Elisabeth, Carlsson Göran, Gustavsson Bengt
Abstract excerpt
PURPOSE: The aim of this study was to examine the clinical significance of the methylenetetrahydrofolate reductase (MTHFR) gene polymorphism C677T in colorectal cancer (CRC). The hypothesis was that the genotype could affect the risk of cancer development and the results of cancer treatment. PATIENTS AND METHODS: Genotyping was made for a random 30% (n = 544) of all patients treated for CRC at our unit from 1999...
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