Article
The new disease models from genetic polymorphisms of Japanese wild mice.
Current pharmaceutical biotechnology - 1 Feb 2009
Matsushima Yoshibumi
Abstract excerpt
Personalized medicine offers a custom-made treatment for each patient directed by information of individual's genetic variation. Despite plenty of information about human single nucleotide polymorphisms (SNPs) and gene expression profile, predicting functions of genetic variations in humans is still a difficult task. Genetic analysis using experimental animals is possible to provide information about the...
Topics
- Animals
- Apolipoproteins E
- Disease Models, Animal
- Hyperlipidemias
- Japan
- Mice
- Mice, Inbred Strains
- Mutation
- Polymorphism, Genetic
- Species Specificity
