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Article

Cyclooxygenase-2 gene polymorphisms reduce the risk of oral premalignant lesions.

Cancer - 1 Apr 2009

Pu Xia, Lippman Scott M, Yang Hushan, Lee J Jack, Wu Xifeng

Abstract excerpt

BACKGROUND: Oral premalignant lesions (OPLs) have the potential to transform into malignant oral cancers. Overexpression of the cyclooxygenase-2 gene (COX-2) is observed frequently in OPLs and oral cancers, suggesting that this gene may play an important role in the progression of oral cancer. Single-nucleotide polymorphisms of COX-2 have been associated with the risk of multiple cancers; however, to date, their...

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Identifiers

PMID: 19197984
DOI: 10.1002/cncr.24157
PMCID: PMC2666299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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