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Article

Spleen tyrosine kinase as a novel candidate tumor suppressor gene for human oral squamous cell carcinoma.

International journal of cancer - 1 Jun 2009

Ogane Satoru, Onda Takeshi, Takano Nobuo, Yajima Tetsuo, Uchiyama Takeshi, Shibahara Takahiko

Abstract excerpt

We analyzed the mutational and methylation status of the spleen tyrosine kinase (Syk) gene and both mRNA and protein levels in primary oral squamous cell carcinoma (OSCC) and OSCC-derived cell lines and examined the function of the Syk gene in OSCC-derived cell lines in vitro. Using quantitative real-time reverse transcription polymerase chain reaction, Western blotting and immunofluorescence on 7 OSCC-derived...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19195024
DOI: 10.1002/ijc.24237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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