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Article

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate.

Rheumatology (Oxford, England) - 1 Jun 2009

Lee Yvonne C, Cui Jing, Costenbader Karen H, Shadick Nancy A, Weinblatt Michael E, Karlson Elizabeth W

Abstract excerpt

OBJECTIVES: We examined the association between candidate single nucleotide polymorphisms (SNPs) and disease activity in RA patients on MTX. METHODS: Our population was drawn from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential Study (BRASS), a prospective, observational cohort of RA patients. A total of 556 participants were genotyped using the Affymetrix 100K platform. Two hundred and sixty-two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19193698
DOI: 10.1093/rheumatology/ken513
PMCID: PMC2681284

Genes

ATIC
CRP
ITPA
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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