Article
Variants of MUC5B minisatellites and the susceptibility of bladder cancer.
DNA and cell biology - 1 Apr 2009
Ahn Eun-Kyung, Kim Wun-Jae, Kwon Jeong-Ah, Choi Phil-Jo, Kim Woo Jin, Sunwoo Yangil, Heo Jeonghoon, Leem Sun-Hee
Abstract excerpt
The human MUC5B gene, which is primarily expressed in the tracheobronchial tract, is clustered to chromosome 11p15.5 with three other secreted gel-forming mucins, MUC6, MUC2, and MUC5AC. In this study, we identified seven variable number of tandem repeats (VNTRs; minisatellites) from the entire MUC5B region. Six (MUC5B-MS1, -MS2, -MS3, -MS4, -MS5, and -MS7) of the seven minisatellites evaluated in this study were...
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