Article
Short rare MUC6 minisatellites-5 alleles influence susceptibility to gastric carcinoma by regulating gene.
Human mutation - 1 Aug 2010
Kwon Jeong-Ah, Lee Sang-Yeop, Ahn Eun-Kyung, Seol So-Young, Kim Min Chan, Kim Su Jin, Kim Seung Il, Chu In-Sun, Leem Sun-Hee
Abstract excerpt
The human MUC6 gene, which is reported to be expressed in the stomach and gall bladder, is clustered on chromosome 11p15.5 with other secreted mucins. In this study, the genomic structure of MUC6 has been analyzed and five VNTR (minisatellites; MS1-MS5) were identified. These minisatellites were analyzed in genomic DNA extracted from 1,103 controls, 470 gastric cancer patients, and multigenerational families....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
