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Article

Association between the length of the MUC8-minisatellite 5 region and susceptibility to chronic obstructive pulmonary disease (COPD).

Genes & genomics - 1 Jan 2018

Lee Se-Ra, Kim Won-Tae, Kim Tae Nam, Nam Jong Kil, Kim Woo Jin, Leem Sun-Hee

Abstract excerpt

In asthma and chronic obstructive pulmonary disease (COPD), mucins display disease-related alterations caused by airway mucus obstruction. MUC5AC, MUC5B and MUC8 are known as the major secretory mucins in human airway epithelial cells. Analysis of mucin genes has identified the presence of several features with a variable number of tandem repeats (VNTR; minisatellites) in the central region of each mucin. In our...

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Identifiers

PMID: 29892905
DOI: 10.1007/s13258-017-0630-8

Genes

MUC8

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