Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The SAAPdb web resource: a large-scale structural analysis of mutant proteins.

Human mutation - 1 Apr 2009

Hurst Jacob M, McMillan Lisa E M, Porter Craig T, Allen James, Fakorede Adebola, Martin Andrew C R

Abstract excerpt

The Single Amino Acid Polymorphism database (SAAPdb) is a new resource for the analysis and visualization of the structural effects of mutations. Our analytical approach is to map single nucleotide polymorphisms (SNPs) and pathogenic deviations (PDs) to protein structural data held within the Protein Data Bank. By mapping mutations onto protein structures, we can hypothesize whether the mutant residues will have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Databases, Protein
Share to Hydrophobic and Hydrophilic Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Internet

Share to Mutation, Missense

Share to Protein Stability

Share to Protein Structure, Quaternary

Share to Proteins

Source

Identifiers

PMID: 19191322
DOI: 10.1002/humu.20898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The SAAPdb web resource: a large-scale structural analysis of mutant proteins.PMID 19191322Read ↗

The SAAP pipeline and database: tools to analyze the impact and predict the pathogenicity of mutations.Semantic proximity Read ↗

MutDB services: interactive structural analysis of mutation data.Semantic proximity Read ↗

Mapping SNPs to protein sequence and structure data.Semantic proximity Read ↗

Analyzing effects of naturally occurring missense mutations.Semantic proximity Read ↗

Mutafy: A webserver to identify high quality mutant protein structures in the Protein Data BankSemantic proximity Read ↗

HPMV: human protein mutation viewer - relating sequence mutations to protein sequence architecture and function changes.Semantic proximity Read ↗

MutDB: update on development of tools for the biochemical analysis of genetic variation.Semantic proximity Read ↗

WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation.Semantic proximity Read ↗

Prediction of impacts of mutations on protein structure and interactions: SDM, a statistical approach, and mCSM, using machine learning.Semantic proximity Read ↗

MutationExplorer: a webserver for mutation of proteins and 3D visualization of energetic impacts.Semantic proximity Read ↗

LS-SNP: large-scale annotation of coding non-synonymous SNPs based on multiple information sources.Semantic proximity Read ↗

SNP@Domain: a web resource of single nucleotide polymorphisms (SNPs) within protein domain structures and sequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.