Article
SNP@Domain: a web resource of single nucleotide polymorphisms (SNPs) within protein domain structures and sequences.
Nucleic acids research - 1 Jul 2006
Han Areum, Kang Hyo Jin, Cho Yoobok, Lee Sunghoon, Kim Young Joo, Gong Sungsam
Abstract excerpt
The single nucleotide polymorphisms (SNPs) in conserved protein regions have been thought to be strong candidates that alter protein functions. Thus, we have developed SNP@Domain, a web resource, to identify SNPs within human protein domains. We annotated SNPs from dbSNP with protein structure-based as well as sequence-based domains: (i) structure-based using SCOP and (ii) sequence-based using Pfam to avoid...
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