Article
Coding variant I62V in the complement factor H gene is strongly associated with polypoidal choroidal vasculopathy.
Ophthalmology - 1 Feb 2009
Kondo Naoshi, Honda Shigeru, Kuno Shin-ichi, Negi Akira
Abstract excerpt
PURPOSE: To investigate whether variants in the complement factor H (CFH) gene are associated with polypoidal choroidal vasculopathy (PCV). DESIGN: Cross-sectional study. PARTICIPANTS: A case-control group of 130 PCV subjects and 173 unrelated controls. METHODS: We conducted an association analysis between CFH variants and PCV in a Japanese population, genotyping 12 tag single nucleotide polymorphisms...
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