Article
Role of RDBP and SKIV2L variants in the major histocompatibility complex class III region in polypoidal choroidal vasculopathy etiology.
Ophthalmology - 1 Aug 2009
Kondo Naoshi, Honda Shigeru, Kuno Shin-ichi, Negi Akira
Abstract excerpt
PURPOSE: To investigate whether polymorphisms in 4 tightly linked genes of the major histocompatibility complex class III--complement component 2 (C2), complement factor B (CFB), RD RNA-binding protein (RDBP), and superkiller viralicidic activity 2-like (SKIV2L)--are associated with polypoidal choroidal vasculopathy (PCV). DESIGN: Cross-sectional study. PARTICIPANTS: A case-control group of 136 PCV subjects and...
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