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Article

Kinetics of genetic switching into the state of bacterial competence.

Biophysical journal - 1 Feb 2009

Leisner Madeleine, Kuhr Jan-Timm, Rädler Joachim O, Frey Erwin, Maier Berenike

Abstract excerpt

Nonlinear amplification of gene expression of master regulators is essential for cellular differentiation. Here we investigated determinants that control the kinetics of the genetic switching process from the vegetative state (B-state) to the competent state (K-state) of Bacillus subtilis, explicitly including the switching window which controls the probability for competence initiation in a cell population. For...

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Source

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Identifiers

PMID: 19186153
DOI: 10.1016/j.bpj.2008.10.034
PMCID: PMC2716573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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