Article
The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2007
Komurcu-Bayrak Evrim, Onat Altan, Poda Mehves, Humphries Steve E, Acharya Jayshree, Hergenc Gülay, Coban Neslihan, Can Gunay, Erginel-Unaltuna Nihan
Abstract excerpt
BACKGROUND: We evaluated the relationship of the lipoprotein lipase (LPL) S447X variant with serum lipid levels and the metabolic syndrome (MS) in the Turkish Adult Risk Factor (TARF) study. This is the first study examining this LPL variant in the Turkish population. METHODS: The sample comprised 1586 Turkish adults. Genotyping was performed using the Taqman allelic discrimination assay. RESULTS: The X447 allele...
Topics
- Aged
- Blood Glucose
- Cholesterol
- Cholesterol, HDL
- Cholesterol, LDL
- Female
- Gene Frequency
- Genotype
- Humans
- Lipids
- Lipoprotein Lipase
- Male
- Metabolic Syndrome
- Middle Aged