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Article

Identification of the ice-binding face of a plant antifreeze protein.

FEBS letters - 18 Feb 2009

Middleton Adam J, Brown Alan M, Davies Peter L, Walker Virginia K

Abstract excerpt

The antifreeze protein of Lolium perenne, a perennial ryegrass, was previously modeled as a beta-roll with two extensive flat beta-sheets on opposite sides of the molecule. Here we have validated the model with a series of nine site-directed steric mutations in which outward-pointing short side-chain residues were replaced by tyrosine. None of these disrupted the fold. Mutations on one of the beta-sheets and on...

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Source

Identifiers

PMID: 19185572
DOI: 10.1016/j.febslet.2009.01.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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