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Article

Analysis of Hepatitis C Virus Infection Models with Hepatocyte Homeostasis

1 Jan 2009

Abstract excerpt

Recently, we developed a model for hepatitis C virus (HCV) infection that explicitly includes proliferation of infected and uninfected hepatocytes. The model predictions agree with a large body of experimental observations on the kinetics of HCV RNA change during acute infection, under antiviral therapy, and after the cessation of therapy. Here we mathematically analyze and characterize both the steady state and...

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PMID: 19183708
DOI: 10.1137/080714579

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