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Article

Triphasic decline of hepatitis C virus RNA during antiviral therapy

27 Jun 2007

Abstract excerpt

UNLABELLED: When patients chronically infected with hepatitis C virus (HCV) are placed on antiviral therapy with pegylated interferon (IFN)-alpha or IFN-alpha plus ribavirin (RBV), HCV RNA generally declines in a biphasic manner. However, a triphasic decline has been reported in a subset of patients. A triphasic decline consists of a first phase (1-2 days) with rapid virus load decline, followed by a "shoulder...

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PMID: 17596864
DOI: 10.1002/hep.21657

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