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Article

Illegitimate transcription. Application to the analysis of truncated transcripts of the dystrophin gene in nonmuscle cultured cells from Duchenne and Becker patients.

The Journal of clinical investigation - 1 Oct 1991

Chelly J, Gilgenkrantz H, Hugnot J P, Hamard G, Lambert M, Récan D, Akli S, Cometto M, Kahn A, Kaplan J C

Abstract excerpt

We have previously demonstrated that there is a low level of transcription of tissue-specific genes in every cell type. In this study, we have taken advantage of this phenomenon, called illegitimate transcription, to analyze the muscle-type dystrophin mRNA in easily accessible cells such as lymphoid cells, fibroblasts, and peripheral blood cells from Duchenne and Becker muscular dystrophies with known internal...

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Identifiers

PMID: 1918370
DOI: 10.1172/JCI115417
PMCID: PMC295575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Illegitimate transcription. Application to the analysis of truncated transcripts of the dystrophin gene in nonmuscle cultured cells from Duchenne and Becker patients.PMID 1918370Read ↗

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