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Article

[The implementation of personalized treatment for osteoporosis].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics - 1 Nov 2008

Mori Seijiro, Chiba Yuko, Yamamoto Seizo, Hosoi Takayuki, Horiuchi Toshiyuki, Kamimiya Fumi, Tamura Yoshiaki, Araki Atsushi, Ito Hideki

Abstract excerpt

AIM: To establish personalized treatment of osteoporosis. METHODS: A T869-->C polymorphism in exon 1 of the transforming growth factor-beta1 gene, which results in a Leu-->Pro substitution at amino acid 10, is reported to be associated with the rate of bone loss as well as the response to active vitamin D treatment. Therefore, we determined this single nucleotide polymorphism (SNP) to estimate the need of active...

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PMID: 19179799
DOI: 10.3143/geriatrics.45.655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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