Article
[Association of polymorphisms of the transforming growth factor-beta 1 gene with genetic susceptibility to osteoporosis].
Rinsho byori. The Japanese journal of clinical pathology - 1 Sept 2001
Yamada Y, Yokota M
Abstract excerpt
Osteoporosis exhibits a substantial genetic component. Although polymorphisms of a variety of genes have been associated with bone mineral density and genetic susceptibility to osteoporosis, the genes responsible for these traits have not been definitively identified. We have shown that a T869-->C polymorphism of the transforming growth factor-beta 1 gene, which results in a Leu-->Pro substitution at amino acid...
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