Article
[Analysis of association of Col1a1 gene alleles with the development of osteoporosis].
Genetika - 1 Dec 2002
Moskalenko M V, Aseev M V, Zazerskaia I E, Kotova S M, Ivashchenko T E, Baranov V S
Abstract excerpt
Allele frequencies of the G-->T polymorphism at the regulatory region of the Collal gene in the population of the northwestern Russia (control group) and in osteoporotic patients were estimated by the RFLP method based on PCR-mediated site-directed mutagenesis. Three patient groups with radiologically confirmed osteoporosis were examined. Group 1 consisted of 64 patients with severe osteoporosis complicated by...
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