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Article

Regulation of the SOS response in Bacillus subtilis: evidence for a LexA repressor homolog.

Journal of bacteriology - 1 Oct 1991

Wojciechowski M F, Peterson K R, Love P E

Abstract excerpt

The inducible SOS response for DNA repair and mutagenesis in the bacterium Bacillus subtilis resembles the extensively characterized SOS system of Escherichia coli. In this report, we demonstrate that the cellular repressor of the E. coli SOS system, the LexA protein, is specifically cleaved in B. subtilis following exposure of the cells to DNA-damaging treatments that induce the SOS response. The in vivo...

Topics

Bacillus subtilis
Bacterial Proteins
Cloning, Molecular
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Gene Expression Regulation, Bacterial
Immunoblotting
Kinetics
Mitomycin
Mutation
Peptide Fragments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rec A Recombinases

Recombinant Fusion Proteins

SOS Response, Genetics

Serine Endopeptidases

beta-Galactosidase

Source

Open in PubMed Open full text

Identifiers

PMID: 1917874
DOI: 10.1128/jb.173.20.6489-6498.1991
PMCID: PMC208985

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1917874-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Regulation of the SOS response in Bacillus subtilis: evidence for a LexA repressor homolog.PMID 1917874Read ↗

The SOS system.Semantic proximity Read ↗

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Genetic evidence for the requirement of RecA loading activity in SOS induction after UV irradiation in Escherichia coli.Semantic proximity Read ↗

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Binding of the Bacillus subtilis LexA protein to the SOS operator.Semantic proximity Read ↗

Novel mechanism for UV sensitivity and apparent UV nonmutability of recA432 mutants: persistent LexA cleavage following SOS induction.Semantic proximity Read ↗

Effect of the recU suppressors sms and subA on DNA repair and homologous recombination in Bacillus subtilis.Semantic proximity Read ↗

Mutant LexA proteins with an increased rate of in vivo cleavage.Semantic proximity Read ↗

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Genetic recombination in Bacillus subtilis 168: effects of recU and recS mutations on DNA repair and homologous recombination.Semantic proximity Read ↗

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