Article
Altering the chromatin landscape for nucleotide excision repair.
Mutation research - 1 Jan 2000
Nag Ronita, Smerdon Michael J
Abstract excerpt
DNA acts as a 'workbench' for various nuclear processes that occur inside living cells. In eukaryotic cells, DNA is highly compacted in a structural hierarchy with histones and other proteins into chromatin. This compaction affects DNA structure and coordinates the accessibility to site-specific nuclear factors during DNA processing events. DNA repair is no exception to this general rule and several reviews have...
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