Article
What are microarrays teaching us about sleep?
Trends in molecular medicine - 1 Feb 2009
Mackiewicz Miroslaw, Zimmerman John E, Shockley Keith R, Churchill Gary A, Pack Allan I
Abstract excerpt
Many fundamental questions about sleep remain unanswered. The presence of sleep across phyla suggests that it must serve a basic cellular and/or molecular function. Microarray studies, performed in several model systems, have identified classes of genes that are sleep-state regulated. This has led to the following concepts: first, a function of sleep is to maintain synaptic homeostasis; second, sleep is a stage...
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