Phenotypic inhibition of the renin-angiotensin system, emergence of the Ren-2 gene, and adaptive radiation of mice.

doi:10.1016/0016-6480(91)90035-5

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Article

Phenotypic inhibition of the renin-angiotensin system, emergence of the Ren-2 gene, and adaptive radiation of mice.

General and comparative endocrinology - 1 Aug 1991

Weaver D, Skinner S, Walker L, Sangster M

Abstract excerpt

The renin-angiotensin system in sub-genus Mus displays unique features including duplication of the renin gene in most strains, strong expression of the second gene in submandibular gland of males, and inhibited responses to injected renin. Our findings indicate that this inhibition results from...

Topics

Angiotensinogen
Animals
Blood Pressure
Female
Kidney
Male
Mice
Mice, Inbred BALB C
Muridae
Nephrectomy
Phenotype
Renin
Renin-Angiotensin System
Salivary Glands
Species Specificity

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