Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation

21 Jan 2009

Abstract excerpt

Islet or beta cell transplantation provides a promising cure for type 1 diabetes patients, but insulin-independency decreases frequently over time. Immunosuppressive regimens are implemented attempting to cope with both auto- and alloimmunity after transplantation. We analysed the influence of different immunotherapies on autoreactive and alloreactive T cell patterns and transplant outcome. Patients receiving...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Diabetes Management and Research
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19161445
DOI: 10.1111/j.1365-2249.2008.03812.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantationPMID 19161445Read ↗

Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 DiabetesSemantic proximity Read ↗

Proinsulin-specific T regulatory cells may control immune responses in type 1 diabetes: implications for adoptive therapy.Semantic proximity Read ↗

HLA class I sensitization in islet transplant recipients: report from the Collaborative Islet Transplant Registry.Semantic proximity Read ↗

Allosensitization of islet allograft recipients.Semantic proximity Read ↗

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects.Semantic proximity Read ↗

Autoreactive T cell profiles are altered following allogeneic islet transplantation with alemtuzumab induction and re-emerging phenotype is associated with graft function.Semantic proximity Read ↗

Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans.Semantic proximity Read ↗

T-cell reactivity to beta-cell antigens in human insulin-dependent (type 1) diabetes mellitus. Implications for diagnosis and therapy.Semantic proximity Read ↗

Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity.Semantic proximity Read ↗

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetesSemantic proximity Read ↗

Differential Impact of T-bet and IFNγ on Pancreatic Islet Allograft Rejection.Semantic proximity Read ↗

Factors affecting long-term efficacy of T regulatory cell-based therapy in type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.