Article
Evaluation of CAND2 and WNT7a as candidate genes for congenital idiopathic clubfoot.
Clinical orthopaedics and related research - 1 May 2009
Shyy William, Dietz Frederick, Dobbs Matthew B, Sheffield Val C, Morcuende Jose A
Abstract excerpt
Congenital idiopathic clubfoot is a common pediatric musculoskeletal deformity with no known etiology. The deformity reportedly follows a Mendelian pattern of inheritance. Recent work has demonstrated linkage in chromosome 3 and 13 in a large, multigeneration, highly penetrant family with idiopathic clubfoot. From the linkage region on chromosome 3, we selected the candidate genes CAND2 and WNT7a, which are...
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