Article
The genetics of idiopathic clubfoot.
Clinical orthopaedics and related research - 1 Aug 2002
Dietz Fred
Abstract excerpt
Idiopathic clubfoot is an uncommon congenital deformity that clusters in families but does not fit typical Mendelian inheritance patterns. Studies done on twins, different incidences in various ethnic groups, and transmission between generations all suggest a genetic component to clubfoot causation. Complex segregation analysis strongly supports the hypothesis that one major gene is responsible for a large...
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