Article
Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.
Journal of pediatric orthopedics - 1 Jan 2000
Shyy William, Wang Kai, Sheffield Val C, Morcuende Jose A
Abstract excerpt
BACKGROUND: Congenital idiopathic clubfoot is the most common musculoskeletal birth defect that develops during the fetal period, but with no known etiology. MYH 2, 3, 7, and 8 are expressed embryonically or perinatally, the period during which congenital idiopathic clubfoot develops; are all components of Type II muscle, which is consistently decreased in clubfoot patients; and are associated with several muscle...
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