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Article

Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis.

Journal of vascular surgery - 1 Mar 2009

Khandanpour Nader, Willis Gavin, Meyer Felicity J, Armon Matthew P, Loke Yoon K, Wright Anthony J A, Finglas Paul M, Jennings Barbara A

Abstract excerpt

OBJECTIVE: Hyperhomocysteinaemia is associated with peripheral arterial disease (PAD). There are inter-individual variations in the metabolism of homocysteine because of genetic polymorphisms. This study analyzed the role of one polymorphism that is associated with raised homocysteine, as a risk factor for PAD. METHODS: This study considered the association of methylenetetrahydrofolate reductase (MTHFR) C677T...

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Source

Identifiers

PMID: 19157768
DOI: 10.1016/j.jvs.2008.10.004

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis.PMID 19157768Read ↗

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