Article
Mutations in methylenetetrahydrofolate reductase and in cysthationine beta synthase: is there a link to homocysteine levels in peripheral arterial disease?
Molecular biology reports - 1 Jun 2011
Santos Maria E R C, das C L E Silva Francisco, Gomes Karina B, Fernandes Ana Paula M, Freitas Fernanda R, Faria Mayara C, Mota Ana Paula L, Carvalho Maria G
Abstract excerpt
Peripheral arterial disease (PAD) is an atherosclerotic disturbance characterized by a progressive obstruction of lower limb arteries. Many risk factors associated with PAD development have being reported in the literature. The present study aimed to investigate whether mutations in the methylenetetrahydrofolate reductase (MTHFR) or in the cystathionine beta synthase (CBS) genes are associated with higher levels...
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