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Article

Beta-defensin-2 promotes resistance against infection with P. aeruginosa.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2009

Wu Minhao, McClellan Sharon A, Barrett Ronald P, Hazlett Linda D

Abstract excerpt

Corneal infection with Pseudomonas aeruginosa results in corneal perforation in susceptible C57BL/6 (B6) mice, but not in resistant BALB/c mice. To explore the role of two important defensins, murine beta-defensin-1 (mBD1) and mBD2, in the ocular immune defense system, their mRNA and protein expression levels were tested by real-time RT-PCR and Western blot, respectively. mRNA, protein, and immunostaining data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19155510
DOI: 10.4049/jimmunol.182.3.1609

Genes

MIP
TLR2
TLR4
TLR9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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