Article
Regulation of Notch and Wingless signalling by phyllopod, a transcriptional target of the EGFR pathway.
The EMBO journal - 18 Feb 2009
Nagaraj Raghavendra, Banerjee Utpal
Abstract excerpt
Spatial and temporal control of Notch and Wingless (Wg) pathways during development is regulated at multiple levels. Here, we present an analysis of Phyllopod as a coordinated regulator of these two critical signal transduction pathways. Phyl specifically helps traffic Notch and Wg pathway components within early endocytic vesicles, thereby controlling the amount of processed signal available for causing a...
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