Article
Association between a literature-based genetic risk score and cardiovascular events in women.
JAMA - 17 Feb 2010
Paynter Nina P, Chasman Daniel I, Paré Guillaume, Buring Julie E, Cook Nancy R, Miletich Joseph P, Ridker Paul M
Abstract excerpt
CONTEXT: While multiple genetic markers associated with cardiovascular disease have been identified by genome-wide association studies, their aggregate effect on risk beyond traditional factors is uncertain, particularly among women. OBJECTIVE: To test the predictive ability of a literature-based genetic risk score for cardiovascular disease. DESIGN, SETTING, AND PARTICIPANTS: Prospective cohort of 19,313...
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