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Article

The non-coding RNA gadd7 is a regulator of lipid-induced oxidative and endoplasmic reticulum stress.

The Journal of biological chemistry - 20 Mar 2009

Brookheart Rita T, Michel Carlos I, Listenberger Laura L, Ory Daniel S, Schaffer Jean E

Abstract excerpt

In obesity and diabetes, an imbalance in fatty acid uptake and fatty acid utilization leads to excess accumulation of lipid in non-adipose tissues. This lipid overload is associated with cellular dysfunction and cell death, which contribute to organ failure, a phenomenon termed lipotoxicity. To e...

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Identifiers

PMID: 19150982
DOI: 10.1074/jbc.M806209200
PMCID: PMC2658040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19150982-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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