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Article

Radiosensitizing Potential of Epigenetic Anticancer Drugs

1 Jan 2009

Abstract excerpt

Over the last few decades, epigenetic tumor changes characterized by promoter hypermethylation and histone modifications have become a topic of intense research. Of particular interest is the potential reversibility of these processes that has led to the development of epigenetic anticancer drugs such as demethylating agents and histone deacetylase inhibitors (HDAC-I). Besides single agent clinical activity in...

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PMID: 19149485
DOI: 10.2174/187152009787047707

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