Article
The enteropathy of prostaglandin deficiency.
Journal of gastroenterology - 1 Jan 2009
Adler David H, Phillips John A, Cogan Joy D, Iverson Tina M, Schnetz-Boutaud Nathalie, Stein Jeffrey A, Brenner David A, Milne Ginger L, Morrow Jason D, Boutaud Oliver, Oates John A
Abstract excerpt
BACKGROUND: Small intestinal ulcers are frequent complications of therapy with nonsteroidal anti-inflammatory drugs (NSAIDs). We present here a genetic deficiency of eicosanoid biosynthesis that illuminates the mechanism of NSAID-induced ulcers of the small intestine. METHODS: Eicosanoids and met...
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