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Article

Antithrombin deficiency and its laboratory diagnosis.

Clinical chemistry and laboratory medicine - 1 Dec 2010

Muszbek László, Bereczky Zsuzsanna, Kovács Bettina, Komáromi István

Abstract excerpt

Antithrombin (AT) belongs to the serpin family and is a key regulator of the coagulation system. AT inhibits active clotting factors, particularly thrombin and factor Xa; its absence is incompatible with life. This review gives an overview of the protein and gene structure of AT, and attempts to explain how glucosaminoglycans, such as heparin and heparan sulfate accelerate the inhibitory reaction that is...

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PMID: 21062218
DOI: 10.1515/CCLM.2010.368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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