Regulation of the pyrimidine salvage pathway by the FUR1 gene product of Saccharomyces cerevisiae.

doi:10.1007/BF00309592

Back to search

Article

Regulation of the pyrimidine salvage pathway by the FUR1 gene product of Saccharomyces cerevisiae.

Current genetics - 1 May 1991

Kern L, de Montigny J, Lacroute F, Jund R

Abstract excerpt

In Saccharomyces cerevisiae, the protein encoded by the FUR1 gene is absolutely required for the expression of uracil phosphoribosyl transferase activity. The occurrence of semi-dominant mutations for 5-fluorouracil-(5FU)-resistance at this locus led us to clone and sequence the semi-dominant fur...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Drug Resistance, Microbial
Fluorouracil
Gene Expression
Genes, Fungal
Molecular Sequence Data
Pentosyltransferases
Plasmids
Pyrimidines
RNA, Fungal
Saccharomyces cerevisiae
Transcription, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.