Article
Interleukin-18 promoter polymorphisms and the disease progression of Hepatitis B virus-related liver disease.
Translational research : the journal of laboratory and clinical medicine - 1 Feb 2009
Migita Kiyoshi, Sawakami-Kobayashi Kazumi, Maeda Yumi, Nakao Kazuhiko, Kondoh Susumu, Sugiura Mika, Kawasumi Ryoko, Segawa Osamu, Tajima Hideji, Machida Masayuki, Nakamura Minoru, Yano Koji, Abiru Seigo, Kawasaki Eiji, Yatsuhashi Hiroshi, Eguchi Katsumi, Ishibashi Hiromi
Abstract excerpt
In this study, we aimed to explore whether interleukin-18 (IL-18) gene-promoter polymorphisms are associated with the outcome of hepatitis B virus (HBV) infection. In all, 204 chronically HBV-infected patients were recruited in this study. Of the 204 HBV-infected patients, 43 were considered to be inactive HBV carriers based on the sustained normalization of serum alanine aminotransferase (ALT) together with...
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