Article
A non-synonymous single-nucleotide polymorphism in the gene encoding Toll-like Receptor 3 (TLR3) is associated with sero-negative rheumatoid arthritis (RA) in a Danish population.
BMC research notes - 10 Oct 2014
Laska Magdalena J, Hansen Bettina, Troldborg Anne, Lorenzen Tove, Stengaard-Pedersen Kristian, Junker Peter, Nexø Bjørn A, Lindegaard Hanne M
Abstract excerpt
BACKGROUND: It has been suggested that polymorphisms in Toll-like Receptors (TLRs) are associated with Rheumatoid Arthritis (RA), but the implicated alleles have differed between studies. The aim of this investigation was to explore whether polymorphisms of TLR genes are associated with RA in a predominantly Caucasian population from Denmark using a case-control approach. FINDINGS: DNA samples (3 university...
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