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Article

Complement consumption in children with Plasmodium falciparum malaria

9 Jan 2009

Abstract excerpt

BACKGROUND: Complement (C) can be activated during malaria, C components consumed and inflammatory mediators produced. This has potential to impair host innate defence. METHODS: In a case-control study, C activation was assessed by measuring serum haemolytic activity (CH50), functional activity of each pathway and levels of C3a, C4a and C5a in children presenting at Kisumu District Hospital, western Kenya, with...

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PMID: 19134190
DOI: 10.1186/1475-2875-8-7

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