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Article

Complement activation in experimental human malaria infection

4 May 2007

Abstract excerpt

The objective of this study was to investigate complement activation in uncomplicated, early phases of human malaria. Fifteen healthy volunteers were experimentally infected with Plasmodium falciparum malaria. Parasitemia and complement activation products were assessed. During blood stage parasitemia, volunteers showed a significant increase in soluble terminal complement complex (TCC) formation. After start of...

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PMID: 17481680
DOI: 10.1016/j.trstmh.2007.02.023

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