Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria In Vitro: Potential Implications for Placental Malaria

23 Mar 2009

Abstract excerpt

BACKGROUND: Placental malaria (PM) is a leading cause of maternal and infant mortality. Although the accumulation of parasitized erythrocytes (PEs) and monocytes within the placenta is thought to contribute to the pathophysiology of PM, the molecular mechanisms underlying PM remain unclear. Based on the hypothesis that excessive complement activation may contribute to PM, in particular generation of the potent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement system in diseases
Share to Iron Metabolism and Disorders
Share to Malaria Research and Control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19308263
DOI: 10.1371/journal.pone.0004953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria In Vitro: Potential Implications for Placental MalariaPMID 19308263Read ↗

Complement 5a-mediated trophoblasts dysfunction is involved in the development of pre-eclampsia.Semantic proximity Read ↗

Complement consumption in children with Plasmodium falciparum malariaSemantic proximity Read ↗

Complement Activation and the Resulting Placental Vascular Insufficiency Drives Fetal Growth Restriction Associated with Placental MalariaSemantic proximity Read ↗

VAR2CSA-Mediated Host Defense Evasion of Plasmodium falciparum Infected Erythrocytes in Placental MalariaSemantic proximity Read ↗

Molecular Principles of Intrauterine Growth Restriction in Plasmodium Falciparum InfectionSemantic proximity Read ↗

Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria.Semantic proximity Read ↗

Multiplexed quantitative proteomics provides mechanistic cues for malaria severity and complexitySemantic proximity Read ↗

Platelet disturbances correlate with endothelial cell activation in uncomplicated <i>Plasmodium vivax</i> malariaSemantic proximity Read ↗

Malaria in pregnancy: pathogenesis and immunitySemantic proximity Read ↗

Triggering receptor expressed on myeloid cells 1 (TREM-1) and cytokine gene variants in complicated and uncomplicated malaria.Semantic proximity Read ↗

A meta-analysis of the endothelial protein C receptor rs867186 genotype in malariaSemantic proximity Read ↗

Reduced Immune Complex Binding Capacity and Increased Complement Susceptibility of Red Cells from Children with Severe Malaria-Associated AnemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.