Article
The TIR domain of TIR-NB-LRR resistance proteins is a signaling domain involved in cell death induction.
Molecular plant-microbe interactions : MPMI - 1 Feb 2009
Swiderski Michal R, Birker Doris, Jones Jonathan D G
Abstract excerpt
In plants, the TIR (toll interleukin 1 receptor) domain is found almost exclusively in nucleotide-binding (NB) leucine-rich repeat resistance proteins and their truncated homologs, and has been proposed to play a signaling role during resistance responses mediated by TIR containing R proteins. Transient expression in Nicotiana benthamiana leaves of "TIR + 80", the RPS4 truncation without the NB-ARC domain, leads...
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