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Article

The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2003

Kelly Michele A, Low Malcolm J, Phillips Tamara J, Wakeland Edward K, Yanagisawa Masashi

Abstract excerpt

Performance in the open field and rotarod paradigms, two common assessments of locomotor function, have been demonstrated to be strain dependent in mice. In this study, eight significant quantitative trait loci (QTL) for behavior phenotypes in either the open field or rotarod paradigms were identified between the 129S6 (129/SvEvTac) and C57BL/6J strains. These strains were chosen for comparison because of their...

Read the complete abstract on PubMed

Topics

Animals
Chromosome Mapping
Female
Genetic Linkage
Genetic Markers
Genome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred C57BL

Models, Genetic

Motor Activity

Movement

Phenotype

Quantitative Trait Loci

Quantitative Trait, Heritable

Species Specificity

Time Factors

Source

Identifiers

PMID: 14694905
DOI: 10.1007/s00335-003-2273-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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