Article
Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.
Cancer - 15 Feb 2009
Vilkin Alex, Niv Yaron, Nagasaka Takeshi, Morgenstern Sarah, Levi Zohar, Fireman Zvi, Fuerst Florentine, Goel Ajay, Boland C Richard
Abstract excerpt
BACKGROUND: The molecular mechanisms that underlie colorectal cancer (CRC) include microsatellite instability (MSI), chromosomal instability, and the CpG island methylator phenotype. There is evidence to suggest that CRC incidence varies among different ethnic populations worldwide. The authors of this report hypothesized that environmental factors and lifestyle differences among various ethnic groups may...
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