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Article

Carbamazepine hypersensitivity syndrome triggered by a human herpes virus reactivation in a genetically predisposed patient.

International archives of allergy and immunology - 1 Jan 2009

Calligaris Lorenzo, Stocco Gabriele, De Iudicibus Sara, Marino Sara, Decorti Giuliana, Barbi Egidio, Carrozzi Marco, Marchetti Federico, Bartoli Fiora, Ventura Alessandro

Abstract excerpt

A case of severe hypersensitivity syndrome, triggered by carbamazepine in the presence of a concomitant active human herpes virus (HHV) 6 and 7 infection is described. To further understand the molecular mechanism of this adverse reaction, analyses of the genetic variants of human leukocyte antigen (HLA) and of the epoxide hydrolase gene (EPHX1), previously associated with carbamazepine hypersensitivity, were...

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Source

Identifiers

PMID: 19127076
DOI: 10.1159/000189202

Genes

EPHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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